Proportional exponentiated link transformed hazards (ELTH) models for discrete time survival data with application.

TitleProportional exponentiated link transformed hazards (ELTH) models for discrete time survival data with application.
Publication TypeJournal Article
Year of Publication2016
AuthorsJoeng, Hee-Koung, Ming-Hui Chen, and Sangwook Kang
JournalLifetime Data Anal
Volume22
Issue1
Pagination38-62
Date Published2016 Jan
ISSN1572-9249
KeywordsBreast Neoplasms, Computer Simulation, Female, Humans, Likelihood Functions, Models, Statistical, Proportional Hazards Models, Survival Analysis
Abstract

Discrete survival data are routinely encountered in many fields of study including behavior science, economics, epidemiology, medicine, and social science. In this paper, we develop a class of proportional exponentiated link transformed hazards (ELTH) models. We carry out a detailed examination of the role of links in fitting discrete survival data and estimating regression coefficients. Several interesting results are established regarding the choice of links and baseline hazards. We also characterize the conditions for improper survival functions and the conditions for existence of the maximum likelihood estimates under the proposed ELTH models. An extensive simulation study is conducted to examine the empirical performance of the parameter estimates under the Cox proportional hazards model by treating discrete survival times as continuous survival times, and the model comparison criteria, AIC and BIC, in determining links and baseline hazards. A SEER breast cancer dataset is analyzed in details to further demonstrate the proposed methodology.

DOI10.1007/s10985-015-9326-z
Alternate JournalLifetime Data Anal
Original PublicationProportional exponentiated link transformed hazards (ELTH) models for discrete time survival data with application.
PubMed ID25772374
PubMed Central IDPMC4676960
Grant ListCA 74015 / CA / NCI NIH HHS / United States
R01 GM070335 / GM / NIGMS NIH HHS / United States
GM 70335 / GM / NIGMS NIH HHS / United States
P01 CA142538 / CA / NCI NIH HHS / United States
R01 CA074015 / CA / NCI NIH HHS / United States
Project: