Title | Statistical aspect of translational and correlative studies in clinical trials. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Pang, Herbert, and Xiaofei Wang |
Journal | Chin Clin Oncol |
Volume | 5 |
Issue | 1 |
Pagination | 11 |
Date Published | 2016 Feb |
ISSN | 2304-3873 |
Keywords | Biomarkers, Tumor, Clinical Trials as Topic, Humans, Multicenter Studies as Topic, Neoplasms, Prognosis, Research Design, Translational Research, Biomedical |
Abstract | In this article, we describe statistical issues related to the conduct of translational and correlative studies in cancer clinical trials. In the era of personalized medicine, proper biomarker discovery and validation is crucial for producing groundbreaking research. In order to carry out the framework outlined in this article, a team effort between oncologists and statisticians is the key for success. |
DOI | 10.3978/j.issn.2304-3865.2014.07.04 |
Alternate Journal | Chin Clin Oncol |
Original Publication | Statistical aspect of translational and correlative studies in clinical trials. |
PubMed ID | 26932435 |
PubMed Central ID | PMC4780353 |
Grant List | P01 CA142538 / CA / NCI NIH HHS / United States R21 AG042894 / AG / NIA NIH HHS / United States P01CA142538 / CA / NCI NIH HHS / United States |
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