Statistical aspect of translational and correlative studies in clinical trials.

TitleStatistical aspect of translational and correlative studies in clinical trials.
Publication TypeJournal Article
Year of Publication2016
AuthorsPang, Herbert, and Xiaofei Wang
JournalChin Clin Oncol
Volume5
Issue1
Pagination11
Date Published2016 Feb
ISSN2304-3873
KeywordsBiomarkers, Tumor, Clinical Trials as Topic, Humans, Multicenter Studies as Topic, Neoplasms, Prognosis, Research Design, Translational Research, Biomedical
Abstract

In this article, we describe statistical issues related to the conduct of translational and correlative studies in cancer clinical trials. In the era of personalized medicine, proper biomarker discovery and validation is crucial for producing groundbreaking research. In order to carry out the framework outlined in this article, a team effort between oncologists and statisticians is the key for success.

DOI10.3978/j.issn.2304-3865.2014.07.04
Alternate JournalChin Clin Oncol
Original PublicationStatistical aspect of translational and correlative studies in clinical trials.
PubMed ID26932435
PubMed Central IDPMC4780353
Grant ListP01 CA142538 / CA / NCI NIH HHS / United States
R21 AG042894 / AG / NIA NIH HHS / United States
P01CA142538 / CA / NCI NIH HHS / United States
Project: