Title | Estimating effect of environmental contaminants on women's subfecundity for the MoBa study data with an outcome-dependent sampling scheme. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Ding, Jieli, Haibo Zhou, Yanyan Liu, Jianwen Cai, and Matthew P. Longnecker |
Journal | Biostatistics |
Volume | 15 |
Issue | 4 |
Pagination | 636-50 |
Date Published | 2014 Oct |
ISSN | 1468-4357 |
Keywords | Adult, Caprylates, Cohort Studies, Environmental Exposure, Environmental Pollutants, Female, Fertility, Fluorocarbons, Humans, Likelihood Functions, Norway, Pregnancy, Proportional Hazards Models |
Abstract | Motivated by the need from our on-going environmental study in the Norwegian Mother and Child Cohort (MoBa) study, we consider an outcome-dependent sampling (ODS) scheme for failure-time data with censoring. Like the case-cohort design, the ODS design enriches the observed sample by selectively including certain failure subjects. We present an estimated maximum semiparametric empirical likelihood estimation (EMSELE) under the proportional hazards model framework. The asymptotic properties of the proposed estimator were derived. Simulation studies were conducted to evaluate the small-sample performance of our proposed method. Our analyses show that the proposed estimator and design is more efficient than the current default approach and other competing approaches. Applying the proposed approach with the data set from the MoBa study, we found a significant effect of an environmental contaminant on fecundability. |
DOI | 10.1093/biostatistics/kxu016 |
Alternate Journal | Biostatistics |
Original Publication | Estimating effect of environmental contaminants on women's subfecundity for the MoBa study data with an outcome-dependent sampling scheme. |
PubMed ID | 24812419 |
PubMed Central ID | PMC4168316 |
Grant List | UL1 RR025747 / RR / NCRR NIH HHS / United States UO1 NS 047537-01 / NS / NINDS NIH HHS / United States UO1 NS 047537-06A1 / NS / NINDS NIH HHS / United States / ImNIH / Intramural NIH HHS / United States N01-ES-75558 / ES / NIEHS NIH HHS / United States P01 CA142538 / CA / NCI NIH HHS / United States R01 ES021900 / ES / NIEHS NIH HHS / United States |
Estimating effect of environmental contaminants on women's subfecundity for the MoBa study data with an outcome-dependent sampling scheme.
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