Title | UNC-Utah NA-MIC framework for DTI fiber tract analysis. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Verde, Audrey R., Francois Budin, Jean-Baptiste Berger, Aditya Gupta, Mahshid Farzinfar, Adrien Kaiser, Mihye Ahn, Hans Johnson, Joy Matsui, Heather C. Hazlett, Anuja Sharma, Casey Goodlett, Yundi Shi, Sylvain Gouttard, Clement Vachet, Joseph Piven, Hongtu Zhu, Guido Gerig, and Martin Styner |
Journal | Front Neuroinform |
Volume | 7 |
Pagination | 51 |
Date Published | 2014 |
ISSN | 1662-5196 |
Abstract | Diffusion tensor imaging has become an important modality in the field of neuroimaging to capture changes in micro-organization and to assess white matter integrity or development. While there exists a number of tractography toolsets, these usually lack tools for preprocessing or to analyze diffusion properties along the fiber tracts. Currently, the field is in critical need of a coherent end-to-end toolset for performing an along-fiber tract analysis, accessible to non-technical neuroimaging researchers. The UNC-Utah NA-MIC DTI framework represents a coherent, open source, end-to-end toolset for atlas fiber tract based DTI analysis encompassing DICOM data conversion, quality control, atlas building, fiber tractography, fiber parameterization, and statistical analysis of diffusion properties. Most steps utilize graphical user interfaces (GUI) to simplify interaction and provide an extensive DTI analysis framework for non-technical researchers/investigators. We illustrate the use of our framework on a small sample, cross sectional neuroimaging study of eight healthy 1-year-old children from the Infant Brain Imaging Study (IBIS) Network. In this limited test study, we illustrate the power of our method by quantifying the diffusion properties at 1 year of age on the genu and splenium fiber tracts. |
DOI | 10.3389/fninf.2013.00051 |
Alternate Journal | Front Neuroinform |
Original Publication | UNC-Utah NA-MIC framework for DTI fiber tract analysis. |
PubMed ID | 24409141 |
PubMed Central ID | PMC3885811 |
Grant List | R01 NS040068 / NS / NINDS NIH HHS / United States U54 EB005149 / EB / NIBIB NIH HHS / United States R01 MH086633 / MH / NIMH NIH HHS / United States P50 MH064065 / MH / NIMH NIH HHS / United States U54 HD079124 / HD / NICHD NIH HHS / United States P30 HD003110 / HD / NICHD NIH HHS / United States R01 MH070890 / MH / NIMH NIH HHS / United States U01 MH070890 / MH / NIMH NIH HHS / United States R21 AG033387 / AG / NIA NIH HHS / United States R01 HD055741 / HD / NICHD NIH HHS / United States T32 NS007431 / NS / NINDS NIH HHS / United States R01 HD053000 / HD / NICHD NIH HHS / United States R01 NS050568 / NS / NINDS NIH HHS / United States R01 MH091645 / MH / NIMH NIH HHS / United States UL1 RR025747 / RR / NCRR NIH HHS / United States P50 MH078105 / MH / NIMH NIH HHS / United States T32 GM008719 / GM / NIGMS NIH HHS / United States P01 CA142538 / CA / NCI NIH HHS / United States R01 AI067518 / AI / NIAID NIH HHS / United States |
UNC-Utah NA-MIC framework for DTI fiber tract analysis.
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